ORAI2 Antibody

APR17669G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR17669G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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ORAI2 Antibody

品牌	Leading Biology	貨號(hào)	APR17669G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ORAI2 antibody.
分子量	Predicted: 19, 28 kDa Observed: 29 kDa
細(xì)胞定位	Antigen Cellular Localization: Membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	ORAI2; At least two isoforms of ORAI2 are known to exist; this antibody will detect both isoforms. ORAI antibody is predicted not to cross-react with ORAI1 or ORAI3.
亞型	IgG
通用名	C7orf19, CBCIP2, TMEM142B
基因ID	80228
UniProt ID	Q96SN7
功能	Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1.
總結(jié)	ORAI2 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, ICC, E
別名	ORAI2 Antibody: CBCIP2, C7orf19, MEM142B, TMEM142B, CBCIP2, PP1729, Protein orai-2, CAP-binding protein complex-interacting protein 2, ORAI calcium release-activated calcium modulator 2
圖像	Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 μg/mL. Immunocytochemistry of ORAI2 in Jurkat cells with ORAI2 antibody at 5 μg/mL. Immunofluorescence of ORAI2 in Jurkat cells with ORAI2 antibody at 20 μg/mL.
說(shuō)明書(shū)	Product Datasheet Protocol
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