Neuritin Antibody

AMM06620G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06620G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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Neuritin Antibody

品牌	Leading Biology	貨號	AMM06620G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neuritin antibody.
分子量	Predicted: 16 kDa Observed: 15 kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. Cell junction, synapse
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	NRN1;
亞型	IgG
通用名	NRN
基因ID	51299
UniProt ID	Q9NPD7
功能	Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
總結(jié)	Neuritin Antibody: As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
別名	Neuritin Antibody: NRN, dJ380B8.2, NRN, Neuritin, neuritin 1
圖像	Western blot analysis of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 μg/mL. Immunohistochemistry of Neuritin in mouse heart tissue with Neuritin antibody at 5 μg/mL. Immunofluorescence of Neuritin in Mouse Heart cells with Neuritin antibody at 20 μg/mL.
說明書	Product Datasheet Protocol
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