全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07643G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RPA Interacting Protein antibody.
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分子量 |
24784 Da
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細胞定位 |
Antigen Cellular Localization:
Isoform 1: Cytoplasm. Nucleus.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
RPAIN;
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亞型 |
IgG
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通用名 |
RIP
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基因ID |
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UniProt ID |
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功能 |
Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.
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總結(jié) |
RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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別名 |
RPA Interacting Protein Antibody: RIP, HRIP, RIP, RPA-interacting protein, hRIP, RPA interacting protein
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圖像 |
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說明書 |
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數(shù)量 |
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