Lipe Antibody

APR08243G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR08243G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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Lipe Antibody

品牌	Leading Biology	貨號(hào)	APR08243G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Lipe antibody.
分子量	Predicted: 85, 90, 110, 118 kDa Observed: 90 kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	LIPE; Multiple isoforms of Lipe are known to exist.
亞型	IgG
基因ID	3991
UniProt ID	Q05469
功能	In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
總結(jié)	Lipe Antibody: Although initially described as an adipocyte-specific triacylglycerol lipase, Lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of Lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that Lipe plays a major role in adipocyte proliferation.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
別名	Lipe Antibody: HSL, LHS, Hormone-sensitive lipase, HSL, lipase, hormone-sensitive
圖像	Western blot analysis of Lipe in human lymph node tissue lysate with Lipe antibody at (A) 0.5 and (B) 1 μg/mL. Immunohistochemistry of lipe in human lymph node tissue with lipe antibody at 2.5 μg/mL. Immunofluorescence of Lipe in Human Lymph Node cells with Lipe antibody at 20 μg/mL.
說(shuō)明書(shū)	Product Datasheet Protocol
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