品牌 |
Leading Biology | 貨號(hào) |
APR15630G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTRP2 antibody.
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分子量 |
29952 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
C1QTNF2; These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
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亞型 |
IgG
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通用名 |
CTRP2
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基因ID |
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UniProt ID |
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總結(jié) |
CTRP2 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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別名 |
CTRP2 Antibody: CTRP2, zacrp2, CTRP2, UNQ6349/PRO21054, Complement C1q tumor necrosis factor-related protein 2, C1q and tumor necrosis factor related protein 2
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圖像 |
Western blot of recombinant CTRP2: (A) 5 ng, (B) 25 ng, and (C) 50 ng with CTRP2 at 1 μg/mL. Immunocytochemistry of CTRP2 in Jurkat cells with CTRP2 antibody at 10 μg/mL. Immunofluorescence of CTRP2 in Jurkat cells with CTRP2 antibody at 20 μg/mL. |
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說(shuō)明書(shū) |
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數(shù)量 |
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