TLR3 Antibody

APR11213G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR11213G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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TLR3 Antibody

品牌	Leading Biology	貨號(hào)	APR11213G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR3 antibody.
分子量	Predicted: 97 kDa Observed: 93 kDa
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	TLR3;
亞型	IgG
基因ID	7098
UniProt ID	O15455
功能	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
總結(jié)	TLR3 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, ICC, E
別名	TLR3 Antibody: CD283, IIAE2, Toll-like receptor 3, toll-like receptor 3
圖像	Western blot analysis of TLR3 in K562 cell lysate with TLR3 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL. Immunocytochemistry of TLR3 in K562 cells with TLR3 antibody at 10 μg/mL. Immunofluorescence of TLR3 in K562 cells with TLR3 antibody at 2 μg/mL.
說明書	Product Datasheet Protocol
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