全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR15634G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTRP4 antibody.
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分子量 |
35256 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
C1QTNF4; These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
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亞型 |
IgG
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通用名 |
CTRP4
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基因ID |
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UniProt ID |
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功能 |
May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production.
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總結(jié) |
CTRP4 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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別名 |
CTRP4 Antibody: CTRP4, ZACRP4, CTRP4, Complement C1q tumor necrosis factor-related protein 4, C1q and tumor necrosis factor related protein 4
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圖像 |
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說明書 |
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數(shù)量 |
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