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TLR2 Antibody

APG02993G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG02993G		0.1 mg / ￥6950

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TLR2 Antibody

品牌	Leading Biology	貨號	APG02993G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR2 antibody.
分子量	89838 Da
細胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應性	Human, Mouse
靶點	TLR2;
亞型	IgG
通用名	TIL4
基因ID	7097
UniProt ID	O60603
功能	Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
總結	TLR2 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, IF, E
別名	TLR2 Antibody: TIL4, CD282, TIL4, Toll-like receptor 2, toll-like receptor 2
圖像	Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1 μg/mL in the presence (A) and absence (B) of its blocking peptide. Immunohistochemical staining of human spleen cells using TLR2 antibody at 2 μg/mL. Immunofluorescence of TLR2 in Human Spleen tissue with TLR2 antibody at 10 μg/mL.
說明書	Product Datasheet Protocol
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