品牌 |
Leading Biology |
貨號(hào) |
APR17033G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLHL1 antibody.
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分子量 |
82680 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Rat
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靶點(diǎn) |
KLHL1;
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亞型 |
IgG
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通用名 |
KIAA1490
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基因ID |
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UniProt ID |
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功能 |
May play a role in organizing the actin cytoskeleton of the brain cells.
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總結(jié) |
KLHL1 Antibody: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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別名 |
KLHL1 Antibody: MRP2, KIAA1490, Kelch-like protein 1, kelch-like 1 (Drosophila)
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圖像 |
Western blot analysis of KLHL1 in human brain cell lysate with KLHL1 antibody at (A) 2 and (B) 4 μg /ml.
Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 μg/mL.
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說明書 |
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數(shù)量 |
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