全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR11456G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ARC antibody.
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分子量 |
Predicted: 23 kDa Observed: 25 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Nucleus, nucleolus. Note=The SR- rich C-terminus mediates nuclear localization Isoform 3: Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
NOL3;
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亞型 |
IgG
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通用名 |
ARC, NOP
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基因ID |
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UniProt ID |
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功能 |
Isoform 1 may be involved in RNA splicing.
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總結(jié) |
ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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別名 |
ARC Antibody: ARC, FCM, MYP, NOP, NOP30, ARC, Nucleolar protein 3, Apoptosis repressor with CARD, Myp, nucleolar protein 3 (apoptosis repressor with CARD domain)
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圖像 |
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說明書 |
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數(shù)量 |
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