品牌 |
Leading Biology | 貨號 |
APR12997G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PSD-95 antibody.
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分子量 |
80495 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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基因ID |
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UniProt ID |
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總結(jié) |
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
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形式 |
Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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別名 |
Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, DLG4, PSD95
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圖像 |
Western blot analysis of rat brain synaptosomal fraction (lanes 1 and 3) and mouse brain lysate (lanes 2 and 4):1, 2. Anti-PSD-95antibody ( APR12997G), (1:200).3, 4. Anti-PSD-95 antibody, preincubated with the control peptide antigen. Expression of PSD-95 in mouse parietal cortex Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti-PSD-95 antibody ( APR12997G), (1:400), followed by anti-rabbit-Cy3 antibody (red). Staining appears mainly in the pyramidal cell body (arrows). Nuclei were stained with DAPI (blue). |
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說明書 |
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數(shù)量 |
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