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TRPC5 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR10561G 50 μl / ￥6950

TRPC5 Antibody

品牌

 Leading Biology

貨號(hào)

 APR10561G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRPC5 antibody.

分子量
111412 Da

宿主
Rabbit

種屬反應(yīng)性
Human, Mouse, Rat

靶點(diǎn)
Peptide (C)HKWGDGQEEQVTTRL,??corresponding to amino acid residues 959-973 of human TRPC5??(Accession number Q9UL62). Intracellular, C-terminus.

基因ID

UniProt ID

總結(jié)
The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel families and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels.1-4The TRPC subfamily consists of seven proteins named TRPC1 to 7 which can be further divided into four subgroups based on their sequence homology and functional similarities:1) TRPC12) TRPC4 and TRPC53) TRPC3, TRPC6, TRPC74) TRPC2.2,5They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues.TRPC5 channels are assumed to form components of store operated channels in some cell types such as salivary gland cells, endothelial cells and vascular smooth muscle cells, and can be activated either by calcium store depletion or by GPCR stimulation pathways.6

形式
Affinity purified antibody, Liquid

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB

稀釋方法
WB~~1:200-1:2000

別名
Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5

圖像

Western blot analysis of rat brain membranes: 1. Anti-TRPC5 antibody ( APR10561G), (1:200). 2. Anti-TRPC5 antibody, preincubated with the control peptide antigen.

Expression of TRPC5 in rat cortex Immunohistochemical staining of rat cortex using Anti-TRPC5 antibody ( APR10561G). A. TRPC5 immunoreactivity (green) appears in pyramidal shaped neuronal soma (vertical arrows) and apical dendrites (horizontal arrows). B. Nuclear staining using DAPI as the counterstain (blue). C. Merged image of A and B.

說(shuō)明書(shū)

數(shù)量

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