P2Y12 Receptor Antibody

APR12677G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12677G		50 μl / ￥6950

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P2Y12 Receptor Antibody

品牌	Leading Biology	貨號(hào)	APR12677G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2Y12 Receptor antibody.
分子量	39439 Da
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	Peptide (C)KTTRPFKTSNPKNLLGAK,?? corresponding to amino acid residues 125-142 of human P2Y12 receptor. (Accession Q9H244). Intracellular, 2nd Cytoplasmic loop.
基因ID	64805
UniProt ID	Q9H244
總結(jié)	The P2Y receptors belong to the G-protein coupled receptors superfamily.They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP AND UDPA. Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.1-3The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shapechange, aggregation, and rise in intracellular Ca2+upon activation.The only other expression of P2Y12 was found in brain, according to results of reversetranscription-polymerase chain reaction and northern blotting.4The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders.4
形式	Affinity purified antibody, Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB
稀釋方法	WB~~1:200-1:2000
別名	P2Y purinoceptor 12, P2Y12, ADP-glucose receptor, ADPG-R, P2T(AC), P2Y(AC), P2Y(cyc), P2Y12 platelet ADP receptor, P2Y(ADP), SP1999, P2RY12, HORK3
圖像	Western blot analysis of rat brain membranes (1, 2) and human platelets (3, 4): 1, 3. Anti-P2Y12 Receptor antibody ( APR12677G), (1:200). 2, 4. Anti-P2Y12 Receptor antibody, preincubated with the control peptide antigen. Expression of P2Y12 in mouse brain Immunohistochemical staining of P2Y12 (red) in mouse brain using Anti-P2Y12 Receptor antibody ( APR12677G). The region shown in this picture is the entorhinal cortex in mouse brain. The P2Y12 positive fibers (arrows) run from the corpus callosum (triangles) into the deep layers of the entorhinal cortex. Sytox green is used as the counterstain.
說(shuō)明書(shū)	Product Datasheet Protocol
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