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Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM06021G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) antibody.
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分子量 |
127179 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Chicken
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種屬反應(yīng)性 |
Human, Mouse, Rat
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通用名 |
CD11B, CR3A
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基因ID |
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UniProt ID |
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功能 |
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
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形式 |
Phosphate-buffered (10 mM) isotonic saline (0.9%, w.v) with sodium azide (0.02%, w/v) added as a preservative.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, ICC
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別名 |
Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, ITGAM, CD11B, CR3A
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圖像 |
Mac-1 staining of the microglial cells in mouse cerebral cortex (red). Photo courtesy of Dr. Felix Eckenstein, University of Vermont. |
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說明書 |
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數(shù)量 |
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