全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06520G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Myelin Basic Protein (MBP) antibody.
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分子量 |
33117 Da
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細胞定位 |
Antigen Cellular Localization:
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin
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宿主 |
Chicken
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種屬反應(yīng)性 |
Human, Mouse, Rat
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基因ID |
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UniProt ID |
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功能 |
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
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形式 |
Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml) in Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS, pH 7.2) with sodium azide (0.02%, w/v).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, ICC
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別名 |
Myelin basic protein, MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein, MBP
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圖像 |
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說明書 |
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數(shù)量 |
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