全部產品分類
品牌 |
Leading Biology | 貨號 |
APG02070G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATG9B antibody (CT).
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分子量 |
101019 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1 and ATG13
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
ATG9B
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亞型 |
Rabbit IgG1
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通用名 |
APG9L2, NOS3AS
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基因ID |
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UniProt ID |
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功能 |
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).
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總結 |
Autophagy, the process of bulk degradation of cellular proteins thro μgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) thro μgh phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IF, ICC, E
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別名 |
Autophagy-related protein 9B, APG9L2, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, NOS3AS
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圖像 |
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說明書 |
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數量 |
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