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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR13153G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Rpsa antibody - N-terminal region.
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分子量 |
32kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C- terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus. Colocalizes with PPP1R16B in the cell membrane (By similarity). 37LRP shuttles to the nucleus upon midkine (MDK) binding. {ECO:0000255|HAMAP-Rule:MF_03016}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog
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通用名 |
Lamr1, P40-8
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基因ID |
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UniProt ID |
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功能 |
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity). Enables malignant tumor cells to penetrate laminin tissue and vessel barriers. Activates precursor thymic anti- OFA/iLRP specific cytotoxic T-cell. May induce CD8 T-suppressor cells secreting IL-10.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}, 37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}, 37LRP {ECO:0000255|HAMAP-Rule:MF_03016}, 37 kDa oncofetal antigen, 37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}, 67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, 67LR {ECO:0000255|HAMAP-Rule:MF_03016}, Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}, LamR {ECO:0000255|HAMAP-Rule:MF_03016}, Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}, LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}, OFA/iLRP, Rpsa, Lamr1, P40-8
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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