品牌 |
Leading Biology |
貨號 |
APR09937G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SIN3B antibody - middle region.
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分子量 |
133kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00810}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog
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通用名 |
KIAA0700
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基因ID |
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UniProt ID |
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功能 |
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b, SIN3B (HGNC:19354), KIAA0700
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圖像 |
WB Suggested Anti-SIN3B Antibody Titration: 0.2-1 μg/ml
ELISA Titer: 1:62500
Positive Control: HCT15 cell lysate
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說明書 |
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數(shù)量 |
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