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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > SIGIRR antibody - C-terminal region品牌 |
Leading Biology | 貨號(hào) |
AMM07799G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SIGIRR antibody - C-terminal region.
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分子量 |
25kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type III membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog
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基因ID |
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UniProt ID |
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功能 |
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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別名 |
Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8, TIR8, SIGIRR
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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