品牌 |
Leading Biology | 貨號 |
APR15731G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DGKH antibody - middle region.
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分子量 |
135kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane. Note=Translocated from the cytoplasm to endosomes in response to stress stimuli Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association. Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
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基因ID |
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UniProt ID |
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功能 |
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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別名 |
Diacylglycerol kinase eta, DAG kinase eta, 2.7.1.107, Diglyceride kinase eta, DGK-eta, DGKH
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圖像 |
Sample Type : Adult mouse cortex Primary Antibody Dilution : 1:500 Secondary Antibody : Anti-rabbit-Cy3 Secondary Antibody Dilution : 1:1000 Color/Signal Descriptions : Red: DGKH Cyan: Nissl (Neurons) Gene Name : DGKH Submitted by : Joshua R. Sanes, Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Room 335, Cambridge MA 02138, Phone: 617-496-8683, FAX: 617-495-0524, email: sanesj@mcb.harvard.edu WB Suggested Anti-DGKH Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: Human heart |
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說明書 |
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數(shù)量 |
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