品牌 |
Leading Biology | 貨號 |
APR15452G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CISD2 antibody - N-terminal region.
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分子量 |
15kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Bovine, Guinea Pig, Dog
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通用名 |
CDGSH2, ERIS, ZCD2
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基因ID |
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UniProt ID |
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功能 |
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
CDGSH iron-sulfur domain-containing protein 2, Endoplasmic reticulum intermembrane small protein, MitoNEET-related 1 protein, Miner1, Nutrient-deprivation autophagy factor-1, NAF-1, CISD2, CDGSH2, ERIS, ZCD2
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圖像 |
WB Suggested Anti-CISD2 Antibody Titration: 0.2-1 μg/ml Positive Control: Transfected 293T |
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說明書 |
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數(shù)量 |
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