品牌 |
Leading Biology | 貨號(hào) |
APR17006G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIF2A antibody - middle region.
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分子量 |
80 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Zebrafish, Dog, Guinea Pig, Horse, Bovine
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靶點(diǎn) |
KIF2A plus end-directed microtubule-dependent motor is required for normal brain development. KIF2A may regulate microtubule dynamics during axonal growth and has microtubule depolymerization activity. The protein is implicated in formation of bipolar mitotic spindles. Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
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通用名 |
KIF2, KNS2
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基因ID |
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UniProt ID |
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功能 |
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
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總結(jié) |
This is a rabbit polyclonal antibody against KIF2A. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
Kinesin-like protein KIF2A, Kinesin-2, hK2, KIF2A, KIF2, KNS2
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圖像 |
KIF2A antibody - middle region (APR17006G) in Human 721_B cells using Western Blot WB Suggested Anti-KIF2A Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate KIF2A is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
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說(shuō)明書(shū) |
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數(shù)量 |
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