品牌 |
Leading Biology | 貨號(hào) |
APR09222G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser241 Munc18-1 antibody.
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分子量 |
65 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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靶點(diǎn) |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 conjugated to KLH.
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基因ID |
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UniProt ID |
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總結(jié) |
Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc18-1 is thought to be regulated by phosphorylation.
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形式 |
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:1000
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別名 |
Syntaxin-binding protein 1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, Stxbp1
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圖像 |
Western blot of mouse hippocampus lysate showing specific immunolabeling of the ~65k Munc18-1protein phosphorylated at Ser241. Phosphospecificity is shown in the second lane whereimmunolabeling is blocked by treatment of the lysate with lambda phosphatase (P-tase). |
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說(shuō)明書 |
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數(shù)量 |
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