品牌 |
Leading Biology | 貨號 |
AMM07623G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Ribosomal S6 Kinase 2 antibody.
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分子量 |
90 KDa
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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基因ID |
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UniProt ID |
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總結 |
The p90 ribosomal S6 kinases (RSK)1–4 are downstream membersof the extracellular signal-regulated kinase (ERK)/MAPK cascade.The loss of RSK2 activity inhumans leads to Coffin–Lowrysyndrome, which is characterized by mental retardation andgrowthdeficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonicregulation on G-protein coupled signaling (Sheffler et al., 2006).
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形式 |
Prepared from rabbit serum by affinity purification via chromatography onan affinity column made with the C-terminal peptide used as antigen.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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稀釋方法 |
WB~~ 1:1000
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別名 |
Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase Mpk-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, Rps6ka2, Mapkapk1c, Rsk3
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圖像 |
Western blot of HeLa lysate showing specific immunolabeling of the ~90k RSK2 protein. |
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說明書 |
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數(shù)量 |
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