品牌 |
Leading Biology | 貨號(hào) |
APR12244G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRASP antibody.
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分子量 |
95 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Rat
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靶點(diǎn) |
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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基因ID |
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UniProt ID |
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總結(jié) |
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
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形式 |
Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the C-terminal peptide used as antigen.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:1000
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別名 |
GRIP1-associated protein 1, GRASP-1, Gripap1, Grasp1
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圖像 |
Western blot of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein. |
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說明書 |
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數(shù)量 |
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