品牌 |
Leading Biology | 貨號 |
APR10625G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Tyrosine Hydroxylase antibody.
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分子量 |
60 KDa
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宿主 |
Sheep
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種屬反應(yīng)性 |
Bovine, Human, Mouse, Rat
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靶點 |
SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma.
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基因ID |
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UniProt ID |
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總結(jié) |
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001).
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形式 |
Prepared from sheep serum by affinity purification using a column to which immunogen was coupled. The antibody is predominantly of the IgG1 subclass.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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稀釋方法 |
WB~~ 1:1000
IF~~ 1:1000
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別名 |
Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, Th
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圖像 |
Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~ 60 k tyrosine hydroxylase proteins. Immunostaining of rabbit retina showing specific labeling of tyrosine hydroxylase in green. |
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說明書 |
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數(shù)量 |
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