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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser181 TAO2 Antibody

Phospho-Ser181 TAO2 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM07157G 100 μl / ￥5450

Phospho-Ser181 TAO2 Antibody

品牌

 Leading Biology

貨號(hào)

 AMM07157G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Ser181 TAO2 antibody.

分子量
120 KDa

宿主
Rabbit

種屬反應(yīng)性
Human, Mouse, Rat

靶點(diǎn)
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 conjugated to KLH.

基因ID

UniProt ID

總結(jié)
In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activatesMAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al.,1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO proteinkinases play an essential role in signaling fromphysiological agonists to the stress-responsive p38MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play arole in the mechanism of TAOactivation. The MEK binding domain of TAO isautophosphorylated on both serine and threonineresidues and Ser181is located within this domain.

形式
Prepared from rabbit serum by affinity purification via sequentialchromatography on phospho- and dephosphopeptide affinity columns.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB

稀釋方法
WB~~ 1:1000

別名
Serine/threonine-protein kinase TAO2, Kinase from chicken homolog C, hKFC-C, Prostate-derived sterile 20-like kinase 1, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Thousand and one amino acid protein kinase 2, TAOK2, KIAA0881, MAP3K17, PSK, PSK1

圖像

Western blot of rat cortex lysate showing specific immunolabeling of the ~120k TAO2 phosphorylated at Ser181 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the Ser181 TAO2 antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase.

說明書

數(shù)量

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