全部產品分類
品牌 |
Leading Biology | 貨號 |
APR12014G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GDNF antibody.
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分子量 |
23662 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
GDNF
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亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
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總結 |
Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer. It promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been s μggested that GDNF may play a role in the treatment of Parkinson’s disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, IP
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別名 |
neurotrophic factor GDNF, GDNF, Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor; ATF
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說明書 |
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數量 |
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