PPAR-alpha Antibody

AMR09446G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMR09446G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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PPAR-alpha Antibody

品牌	Leading Biology	貨號(hào)	AMR09446G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPAR-alpha antibody.
分子量	52225 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat, Bovine
靶點(diǎn)	PPARa
亞型	Rabbit IgG
通用名	NR1C1, PPAR
基因ID	5465
UniProt ID	Q07869
功能	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
總結(jié)	PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARα is preferentially expressed in liver, skeletal muscle, heart and kidney. PPARα is involved in regulation of lipid homeostasis. Its ligands include fatty acids, NSAIDs, prostaglandins, leukotriene B4, etc. PPARα transcriptionally regulates a variety of genes for enzymes and proteins involved in fatty acid metabolism and oxidation.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB
別名	PPARA , PPAR , OTTHUMP00000042872 , hPPAR , MGC2452 , OTTHUMP00000028713 , NR1C1 , PPAR-alpha , MGC2237
圖像	1) 80 μg Jurkat cell lysate；2) 40 μg Jurkat cell lysate；3) 100 μg Rat liver lysate；4) 100 μg Rat kidney lysate .Blocking/Dilution buffer: 5% NFDM (1 hr at RT) / TBST E-Selectin Polyclonal Antibody used at 1:1000 dilution - O/N at 4?C.Goat Anti-Rabbit IgG peroxidase conjugated used at 1:10,000 dilution – 1 hr at RT Predicted band size: ~ 52 kDa. (Isoform 1), ~ 19 kDa (Isoform 2). Observed band size: ~ 52 kDa. ~20 kDa cleaved fragment.
說(shuō)明書(shū)	Product Datasheet Protocol
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