品牌 |
Leading Biology | 貨號 |
APG02110G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATP5B / ATP Synthase Beta antibody.
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分子量 |
56560 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
Human ATP5B / ATP Synthase Beta.
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亞型 |
IgG
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通用名 |
ATPMB, ATPSB
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基因ID |
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UniProt ID |
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功能 |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
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總結(jié) |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (5 μg/ml), WB (1:500 - 1:2000),
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別名 |
ATP5B, ATPMB, ATPSB, Beta-mtATPase, F0F1-ATP synthase beta subunit, ATP synthase beta subunit
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圖像 |
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of extracts of various cell lines, using ATP5B antibody. |
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說明書 |
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數(shù)量 |
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