品牌 |
Leading Biology | 貨號 |
AMM06158G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNMB4 antibody (aa86-140).
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分子量 |
23949 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
Human KCNMB4
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基因ID |
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UniProt ID |
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功能 |
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
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總結(jié) |
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (5 μg/ml), WB (1:500 - 1:1000),
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別名 |
KCNMB4, BK beta 4, BK channel subunit beta-4, BKbeta4, Hbeta4, K(VCA)beta-4, Slowpoke beta 4, Maxi K channel subunit beta-4, Maxi K beta 4, Slo-beta-4
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圖像 |
Anti-KCNMB2 antibody IHC staining of human brain, cortex. Human Vascular Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot of MaxiK (K119) pAb in extracts from HepG2 cells. |
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說明書 |
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數(shù)量 |
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