品牌 |
Leading Biology | 貨號 |
APR10539G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRAP1 / HSP75 antibody.
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分子量 |
80110 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion. Mitochondrion inner membrane Mitochondrion matrix
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human TRAP1
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亞型 |
IgG
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通用名 |
HSP75
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基因ID |
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UniProt ID |
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功能 |
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
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總結(jié) |
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (7.5 μg/ml), WB (1:500 - 1:3000),
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別名 |
TRAP1, HSP 75, HSP75, HSP90L, TNFR-associated protein 1, TRAP-1
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圖像 |
Anti-TRAP1 / HSP75 antibody IHC staining of human colon. Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE TRAP1 antibody diluted at 1:3000 |
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說明書 |
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數(shù)量 |
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