CAV1 / Caveolin 1 Antibody (N-Terminus)

APG02440G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG02440G		100 μg / ￥4950

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CAV1 / Caveolin 1 Antibody (N-Terminus)

品牌	Leading Biology	貨號	APG02440G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAV1 / Caveolin 1 antibody (N-Terminus).
分子量	20472 Da
細胞定位	Antigen Cellular Localization: Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Membrane raft Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae
宿主	Goat
種屬反應(yīng)性	Human, Mouse, Dog
靶點	Detects a band of approximately 25 kDa by Western blot in the following cell lysate: hCat, MDCK and 3T3.
亞型	IgG
通用名	CAV
基因ID	857
UniProt ID	Q03135
功能	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
總結(jié)	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF
稀釋方法	IF (1:25 - 1:250), IHC-P (5 μg/ml), WB (1:500 - 1:2000),
別名	CAV1, Caveolin-1, CGL3, CAV, MSTP085, VIP21, BSCL3
圖像	Anti-CAV1 / Caveolin 1 antibody IHC staining of human heart. Immunofluorescence - anti-CAV1 antibody - Caveolae Marker in Hepa1-6 cells at 1:50 dilution. Western blot.
說明書	Product Datasheet Protocol
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