We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DNAJB11 antibody (aa31-80).
分子量
40514 Da
細(xì)胞定位
Antigen Cellular Localization:
Endoplasmic reticulum lumen Note=Associated with the ER membrane in a C-terminally epitope- tagged construct
宿主
Rabbit
種屬反應(yīng)性
Human, Mouse, Rat
靶點
DNAJB11 Antibody detects endogenous levels of total DNAJB11 protein.
Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
總結(jié)
Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
形式
Liquid. In PBS containing 0.02% sodium azide.
儲存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.