全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APG03245G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYSLTR1 / CYSLT1 antibody (aa131-180).
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分子量 |
38541 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
CLTR1 Antibody detects endogenous levels of total CLTR1 protein.
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亞型 |
IgG
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通用名 |
CYSLT1
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基因ID |
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UniProt ID |
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功能 |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
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總結(jié) |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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稀釋方法 |
ELISA (1:10000), IF (1:100 - 1:500), IHC-P (20 μg/ml), WB (1:500 - 1:1000),
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別名 |
CYSLTR1, Cys-LT1 receptor, CysLT(1), Cys-leukotriene-1 receptor, CYSLT1, CYSLT1R, CYSLTR, HG55, LTD4 receptor, HMTMF81, Cysteinyl lt1 receptor
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圖像 |
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說明書 |
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數(shù)量 |
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