品牌 |
Leading Biology | 貨號 |
APR08094G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIAA0652 / ATG13 antibody (C-Terminus).
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分子量 |
57kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
Recognizes human Autophagy-related protein 13 (ATG13), a 517 amino acid protein belonging to the ATG13 metazoan family.
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通用名 |
KIAA0652
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基因ID |
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UniProt ID |
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功能 |
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
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總結 |
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (5 μg/ml), WB (1 μg/ml),
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別名 |
Autophagy-related protein 13, ATG13, KIAA0652
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圖像 |
Western blot of rat heart tissue lysate probed with Rabbit anti-Mouse ATG13 at 1uM in the... Anti-KIAA0652 / ATG13 antibody IHC staining of human prostate. |
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說明書 |
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數(shù)量 |
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