品牌 |
Leading Biology | 貨號(hào) |
APG02987G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TIP30 / HTATIP2 antibody.
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分子量 |
27kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus envelope
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human HTATIP2 / TIP30
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基因ID |
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UniProt ID |
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功能 |
Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
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總結(jié) |
Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, ICC, IP
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稀釋方法 |
ICC (1:100-1:1000), IF (1:100-1:1000), IHC-P (5 μg/ml), IP (1:100-1:500), WB (1:1000-1:10000)
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別名 |
Oxidoreductase HTATIP2, 1.1.1.-, 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2, HTATIP2 (HGNC:16637)
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圖像 |
Anti-TIP30 / HTATIP2 antibody IHC staining of human small intestine. Sample (30 ug of whole cell lysate) A: A431 B: HeLa 12% SDS PAGE HTATIP2 / TIP30 antibody... Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using TIP30... |
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說(shuō)明書(shū) |
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數(shù)量 |
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