CCNT1 / Cyclin T1 Antibody (C-Terminus)

APR11017G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR11017G		50 μg / ￥4950

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CCNT1 / Cyclin T1 Antibody (C-Terminus)

品牌	Leading Biology	貨號(hào)	APR11017G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCNT1 / Cyclin T1 antibody (C-Terminus).
分子量	81kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	Human CCNT1 / Cyclin T1
基因ID	904
UniProt ID	O60563
功能	Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.
總結(jié)	Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
稀釋方法	IF (20 μg/ml), IHC-P (10 μg/ml), WB (1-2 μg/ml)
別名	Cyclin-T1, CycT1, Cyclin-T, CCNT1
圖像	Western blot analysis of CCNT1 in rat brain tissue lysate with CCNT1 antibody at 1 ug/ml in (A)... Immunofluorescence of CCNT1 in rat brain tissue with CCNT1 antibody at 20 ug/ml. Anti-CCNT1 / Cyclin T1 antibody IHC staining of human testis.
說明書	Product Datasheet Protocol
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