全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR07773G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMOX1 / HO-1 antibody.
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分子量 |
33kDa
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細胞定位 |
Antigen Cellular Localization:
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat, Dog
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靶點 |
Detect an ~32kD protein, corresponding to the molecular mass of HO-1 on SDS Page Western Blots.
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通用名 |
HO, HO1
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基因ID |
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UniProt ID |
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功能 |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
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總結(jié) |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P
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稀釋方法 |
IHC-P (5 μg/ml), WB (1:1000),
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別名 |
Heme oxygenase 1, HO-1, 1.14.99.3, HMOX1, HO, HO1
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圖像 |
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說明書 |
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數(shù)量 |
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