品牌 |
Leading Biology | 貨號 |
AMM08554G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZNF521 antibody (N-Terminus).
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分子量 |
148kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
Human ZNF521. ZNF521 antibody is human specific.
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通用名 |
EHZF, LIP3
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.
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總結(jié) |
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, ICC
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稀釋方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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別名 |
Zinc finger protein 521, Early hematopoietic zinc finger protein, LYST-interacting protein 3, ZNF521, EHZF, LIP3
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圖像 |
Immunocytochemistry of ZNF521 (NT) in HeLa cells with ZNF521 (NT) antibody at 2.5 ug/ml. Immunofluorescence of ZNF521 in HeLa cells with ZNF521 antibody at 20 ug/ml. Western blot analysis of ZNF521 in HeLa cell lysate with ZNF521 antibody at 1 ug/ml in (A) the... |
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說明書 |
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數(shù)量 |
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