PLN / Phospholamban Antibody (N-Terminus)

AMR09371G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMR09371G		50 μg / ￥4950

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PLN / Phospholamban Antibody (N-Terminus)

品牌	Leading Biology	貨號(hào)	AMR09371G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLN / Phospholamban antibody (N-Terminus).
分子量	6kDa
細(xì)胞定位	Antigen Cellular Localization: Sarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
宿主	Goat
種屬反應(yīng)性	Human, Mouse, Rat, Rabbit, Monkey, Pig, Horse, Bovine, Dog
靶點(diǎn)	Human PLN / Phospholamban.
通用名	PLB
基因ID	5350
UniProt ID	P26678
功能	Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
總結(jié)	Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	ELISA (1:8000), IHC-P (3.75 μg/ml), WB (0.01-0.03 μg/ml)
別名	Cardiac phospholamban, PLB, PLN, PLB
圖像	PLN antibody (0.03 ug/ml) staining of Human Heart lysate (35 ug protein/ml in RIPA buffer). Anti-PLN / Phospholamban antibody IHC of human heart.
說(shuō)明書	Product Datasheet Protocol
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PLN / Phospholamban Antibody (N-Terminus)