品牌 |
Leading Biology | 貨號 |
AMM06869G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NUMB antibody (aa1-50).
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分子量 |
71kDa
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細胞定位 |
Antigen Cellular Localization:
Membrane; Peripheral membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Monkey, Bovine
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靶點 |
Human NUMB
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
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總結(jié) |
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (5-10 μg/ml), WB (1-2 μg/ml),
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別名 |
Protein numb homolog, h-Numb, Protein S171, NUMB
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圖像 |
Western blot of NUMB in mouse brain lysate in the 1) absence and 2) presence of immunizing... Anti-NUMB antibody IHC of human adrenal. Anti-NUMB antibody IHC of human spleen. |
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說明書 |
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數(shù)量 |
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