KCNIP3 / Dream / Calsenilin Antibody (aa29-78)

AMM06122G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06122G		50 μl / ￥4950

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KCNIP3 / Dream / Calsenilin Antibody (aa29-78)

品牌	Leading Biology	貨號(hào)	AMM06122G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNIP3 / Dream / Calsenilin antibody (aa29-78).
分子量	29kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (By similarity). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	Calsenilin/KCNIP3 antibody detects endogenous levels of total Calsenilin/KCNIP3 protein.
通用名	CSEN, DREAM, KCHIP3
基因ID	30818
UniProt ID	Q9Y2W7
功能	Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
總結(jié)	Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
稀釋方法	ELISA (1:20000), IF (1:100-1:500), IHC-P (10 μg/ml), WB (1:500-1:1000) ,
別名	Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3, KCNIP3, CSEN, DREAM, KCHIP3
圖像	Immunofluorescence of HeLa cells, using Calsenilin/KCNIP3 antibody. Western blot of extracts from MCF-7/Jurkat/A549 cells, using Calsenilin/KCNIP3 antibody. Anti-KCNIP3 / CSEN antibody IHC of human brain, cortex neurons.
說明書	Product Datasheet Protocol
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KCNIP3 / Dream / Calsenilin Antibody (aa29-78)