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HES1 / HES-1 Antibody (N-Terminus)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR12361G 50 μl / ¥4950

HES1 / HES-1 Antibody (N-Terminus)

品牌

Leading Biology

貨號(hào)

APR12361G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HES1 / HES-1 antibody (N-Terminus).

分子量

30kDa

細(xì)胞定位

Antigen Cellular Localization: Nucleus.

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse, Rat

通用名

BHLHB39, HL, HRY

基因ID

UniProt ID

功能

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

總結(jié)

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

ELISA (1:80000), IHC-P (2.5 μg/ml), WB (1:200-1:1000)

別名

Transcription factor HES-1, Class B basic helix-loop-helix protein 39, bHLHb39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, hHL, HES1, BHLHB39, HL, HRY

圖像

Anti-HES1 antibody IHC of human testis.

說明書

數(shù)量

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