全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17858G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SFRP4 antibody (Internal).
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分子量 |
40kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted. Note=Cytoplasmic in ovarian tumor cells
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog
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靶點 |
Human SFRP4.
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通用名 |
FRPHE
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基因ID |
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UniProt ID |
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功能 |
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
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總結(jié) |
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:16000), IHC-P (3.75 μg/ml), WB (0.3-1 μg/ml)
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別名 |
Secreted frizzled-related protein 4, sFRP-4, Frizzled protein, human endometrium, FrpHE, SFRP4, FRPHE
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圖像 |
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說明書 |
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數(shù)量 |
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