品牌 |
Leading Biology | 貨號 |
APR08044G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IRS1 antibody (aa289-338).
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分子量 |
132kDa
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
IRS1 Antibody detects endogenous levels of total IRS1 protein.
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基因ID |
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UniProt ID |
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功能 |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
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總結 |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P, IF, E
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稀釋方法 |
ELISA (1:1000), IF (1:100-1:500), IHC-P (10 μg/ml)
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別名 |
Insulin receptor substrate 1, IRS-1, IRS1
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圖像 |
Immunofluorescence of COS7 cells, using IRS-1 (Ab-323) Antibody. Anti-IRS1 antibody IHC of human adrenal medulla. |
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說明書 |
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數(shù)量 |
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