全部產品分類
品牌 |
Leading Biology | 貨號 |
APG03175G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATXN1 / SCA1 antibody (aa742-791).
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分子量 |
87kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Colocalizes with USP7 in the nucleus
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse
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靶點 |
Ataxin 1 (Ab-776) Antibody detects endogenous levels of total Ataxin 1 protein.
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通用名 |
ATX1, SCA1
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基因ID |
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UniProt ID |
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功能 |
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
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總結 |
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P, IF, E
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稀釋方法 |
ELISA (1:5000), IF (1:100-1:500), IHC-P (5 μg/ml)
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別名 |
Ataxin-1, Spinocerebellar ataxia type 1 protein, ATXN1, ATX1, SCA1
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圖像 |
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說明書 |
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數(shù)量 |
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