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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > HDAC6 Antibody (aa7-56)

HDAC6 Antibody (aa7-56)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR17780G 50 μl / ¥4950

HDAC6 Antibody (aa7-56)

品牌

Leading Biology

貨號(hào)

APR17780G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HDAC6 antibody (aa7-56).

分子量

131kDa

細(xì)胞定位

Antigen Cellular Localization: Nucleus. Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon. Note=It is mainly cytoplasmic, where it is associated with microtubules

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

HDAC6 (Ab-22) Antibody detects endogenous levels of total HDAC6 protein.

通用名

KIAA0901

基因ID

UniProt ID

功能

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

總結(jié)

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

稀釋方法

ELISA (1:1000), IF (1:100-1:500), IHC-P (5 μg/ml), WB (1:500-1:1000) ,

別名

Histone deacetylase 6, HD6, 3.5.1.98, HDAC6, KIAA0901

圖像

Immunofluorescence of HepG2 cells, using HDAC6 (Ab-22) Antibody.

Western blot of extracts from HepG2 cells, using HDAC6 (Ab-22) Antibody.

Anti-HDAC6 antibody IHC of human intestine, ganglion cells.

說明書

數(shù)量

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