品牌 |
Leading Biology |
貨號 |
APG02557G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CFTR antibody (aa2-14).
|
分子量 |
168kDa
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細胞定位 |
Antigen Cellular Localization:
Early endosome membrane; Multi-pass membrane protein. Cell membrane. Note=In the oviduct and bronchus, detected on the apical side of epithelial cells, but not associated with cilia.
|
宿主 |
Goat
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種屬反應(yīng)性 |
Human, Monkey, Sheep, Bovine
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靶點 |
Human CFTR.
|
通用名 |
ABCC7
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基因ID |
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UniProt ID |
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功能 |
Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
|
總結(jié) |
Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
|
形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P
|
稀釋方法 |
IHC-P (2.5-5 μg/ml)
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別名 |
Cystic fibrosis transmembrane conductance regulator, CFTR, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, 3.6.3.49, cAMP-dependent chloride channel, CFTR, ABCC7
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圖像 |
Anti-CFTR antibody IHC of human kidney.
Anti-CFTR antibody IHC of human prostate.
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說明書 |
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數(shù)量 |
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