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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CTMP / THEM4 Antibody (Internal)

CTMP / THEM4 Antibody (Internal)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)
APR15623G 50 μg / ¥4950

CTMP / THEM4 Antibody (Internal)

品牌

Leading Biology

貨號(hào)

APR15623G

產(chǎn)品分類(lèi)

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTMP / THEM4 antibody (Internal).

分子量

27kDa

細(xì)胞定位

Antigen Cellular Localization: Cell membrane. Cell projection, ruffle membrane Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein Mitochondrion intermembrane space. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse, Rat

靶點(diǎn)

Human THEM4

通用名

CTMP

基因ID

UniProt ID

功能

Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.

總結(jié)

Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

稀釋方法

IHC-P (5 μg/ml), WB (1-2 μg/ml),

別名

Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, 3.1.2.2, Carboxyl-terminal modulator protein, Thioesterase superfamily member 4, THEM4, CTMP

圖像

Immunofluorescence of THEM4 in human liver tissue with THEM4 antibody at 20 ug/ml.

Western blot of THEM4 in human liver tissue lysate with THEM4 antibody at (A) 1 and (B) 2 ug/ml.

說(shuō)明書(shū)

數(shù)量

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